Liposome and their applications in cancer therapy

Himanshu Pandey, Radha Rani, Vishnu Agarwal

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

Liposomes, the vesicles of phospholipid bilayer, can encapsulate both hydrophilic and lipophilic drugs and protect them from degradation. Liposomes have been extensively studied and continue to create intense interest in research since their discovery in the mid-1960s. Since then, liposomes have been considered to be the most successful nanocarriers for drug deliver and have made their way to the market. Currently, a number of liposomal formulations are on the marker for cancer treatment and many more are in pipe line. This review discusses about the liposome components, methods of preparation, drug encapsulation mechanism and the potential therapeutic applications of liposomes in cancer therapy.

Original languageEnglish
Article numbere16150477
JournalBrazilian Archives of Biology and Technology
Volume59
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • Cancer
  • Doxil
  • Drug delivery
  • LipoDox
  • Liposomes
  • Myocet

ASJC Scopus subject areas

  • General

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