LiveBench-8: The large-scale, continuous assessment of automated protein structure prediction

Leszek Rychlewski, Daniel Fischer

Research output: Contribution to journalArticlepeer-review

87 Scopus citations

Abstract

We present the results of the evaluation of the latest LiveBench-8 experiment. These results provide a snapshot view of the state of the art in automated protein structure prediction, just before the 2004 CAFASP-4/CASP-6 experiments begin. The last CAFASP/CASP experiments demonstrated that automated meta-predictors entail a significant advance in the field, already challenging most human expert predictors. LiveBench-8 corroborates the superior performance of meta-predictors, which are able to produce useful predictions for over one-half of the test targets. More importantly, LiveBench-8 identifies a handful of recently developed autonomous (nonmeta) servers that perform at the very top, suggesting that further progress in the individual methods has recently been obtained.

Original languageEnglish
Pages (from-to)240-245
Number of pages6
JournalProtein Science
Volume14
Issue number1
DOIs
StatePublished - 1 Jan 2005

Keywords

  • CAFASP
  • LiveBench
  • Protein structure prediction

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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