Immunotherapy using subcutaneous injections of recombinant interleukin-2 (IL-2) and recombinant interferon alpha-2a (IFN-α) for advanced hematologic and solid tumors is rapidly developing. We report five patients with Hodgkin's and non-Hodgkin's lymphoma who developed a local cutaneous reaction consisting of inflammatory painful nodules with a central multiloculated vesicle at the site of sc injections of IL-2 and IFN-α immunotherapy following ABMT. This is the first report of a local cutaneous adverse reaction induced by IL-2 and IFN-α immunotherapy following ABMT.
|Number of pages||4|
|Journal||Bone Marrow Transplantation|
|State||Published - 1 Jan 1993|
ASJC Scopus subject areas