Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT

L. Klapholz; A. Ackerstein; M. A. Goldenhersh; D. Vardy; A. Nagler

Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT

L. Klapholz
, A. Ackerstein
, M. A. Goldenhersh
, D. Vardy
, A. Nagler

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Immunotherapy using subcutaneous injections of recombinant interleukin-2 (IL-2) and recombinant interferon alpha-2a (IFN-α) for advanced hematologic and solid tumors is rapidly developing. We report five patients with Hodgkin's and non-Hodgkin's lymphoma who developed a local cutaneous reaction consisting of inflammatory painful nodules with a central multiloculated vesicle at the site of sc injections of IL-2 and IFN-α immunotherapy following ABMT. This is the first report of a local cutaneous adverse reaction induced by IL-2 and IFN-α immunotherapy following ABMT.

Original language	English
Pages (from-to)	443-446
Number of pages	4
Journal	Bone Marrow Transplantation
Volume	11
Issue number	6
State	Published - 1 Jan 1993
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Hematology
Transplantation

Cite this

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title = "Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT",

abstract = "Immunotherapy using subcutaneous injections of recombinant interleukin-2 (IL-2) and recombinant interferon alpha-2a (IFN-α) for advanced hematologic and solid tumors is rapidly developing. We report five patients with Hodgkin's and non-Hodgkin's lymphoma who developed a local cutaneous reaction consisting of inflammatory painful nodules with a central multiloculated vesicle at the site of sc injections of IL-2 and IFN-α immunotherapy following ABMT. This is the first report of a local cutaneous adverse reaction induced by IL-2 and IFN-α immunotherapy following ABMT.",

author = "L. Klapholz and A. Ackerstein and Goldenhersh, \{M. A.\} and D. Vardy and A. Nagler",

year = "1993",

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language = "English",

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journal = "Bone Marrow Transplantation",

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T1 - Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT

AU - Klapholz, L.

AU - Ackerstein, A.

AU - Goldenhersh, M. A.

AU - Vardy, D.

AU - Nagler, A.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Immunotherapy using subcutaneous injections of recombinant interleukin-2 (IL-2) and recombinant interferon alpha-2a (IFN-α) for advanced hematologic and solid tumors is rapidly developing. We report five patients with Hodgkin's and non-Hodgkin's lymphoma who developed a local cutaneous reaction consisting of inflammatory painful nodules with a central multiloculated vesicle at the site of sc injections of IL-2 and IFN-α immunotherapy following ABMT. This is the first report of a local cutaneous adverse reaction induced by IL-2 and IFN-α immunotherapy following ABMT.

AB - Immunotherapy using subcutaneous injections of recombinant interleukin-2 (IL-2) and recombinant interferon alpha-2a (IFN-α) for advanced hematologic and solid tumors is rapidly developing. We report five patients with Hodgkin's and non-Hodgkin's lymphoma who developed a local cutaneous reaction consisting of inflammatory painful nodules with a central multiloculated vesicle at the site of sc injections of IL-2 and IFN-α immunotherapy following ABMT. This is the first report of a local cutaneous adverse reaction induced by IL-2 and IFN-α immunotherapy following ABMT.

UR - https://www.scopus.com/pages/publications/0027265318

M3 - Article

C2 - 8334424

AN - SCOPUS:0027265318

SN - 0268-3369

VL - 11

SP - 443

EP - 446

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

IS - 6

ER -

Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT

Abstract

UN SDGs

ASJC Scopus subject areas

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