Locally aggressive differentiated thyroid carcinoma

Ferit Tovi, Jed Goldstein

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations


    Local infiltration of adjacent anatomic structures and soft tissues of the neck from well‐differentiated carcinoma of the thyroid gland is a relatively infrequent occurrence. We report our experience with 21 such cases seen in our department over the past 20 years. All patients were treated by total thryoidectomy and total or partial excision of the infiltrated adjacent structures. Papillary carcinoma was the most frequent type of primary tumor seen. Following the definitive surgery, all patients were scanned with radioactive iodine (131I). In case of isotope entrapment, a curative dose 131I was given. All patients in our series were required to receive thyroid hormone replacement. Four patients died as a result of their disease. Uncontrolled local disease and distant metastases were present at the time of death. Three patients died of unrelated causes. Two‐thirds of the patients are still alive (from 1 to 19 years after the treatment).

    Original languageEnglish
    Pages (from-to)99-104
    Number of pages6
    JournalJournal of Surgical Oncology
    Issue number2
    StatePublished - 1 Jan 1985


    • complications of thyroid carcinoma
    • differentiated thyroid carcinomas
    • treatment of thyroid carcinoma

    ASJC Scopus subject areas

    • Surgery
    • Oncology


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