Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: A case-series

K. N. Roy Chengappa; J. Levine; D. Rathore; H. Parepally; R. Atzert

doi:10.1016/S0924-9338(01)00562-4

Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: A case-series

K. N. Roy Chengappa, J. Levine, D. Rathore, H. Parepally, R. Atzert

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

Topiramate is an antiepileptic agent, which is being investigated as a mood-stabilizer. Three obese individuals with DSM-IV bipolar I disorder and type II diabetes mellitus received topiramate treatment in combination with antipsychotics and valproate or carbamazepine. In addition to improved mood stability, these individuals lost between 16 to 20.5% of their pre-topiramate body weight and also achieved significant glycemic control.

Original language	English
Pages (from-to)	186-190
Number of pages	5
Journal	European Psychiatry
Volume	16
Issue number	3
DOIs	https://doi.org/10.1016/S0924-9338(01)00562-4
State	Published - 1 Jan 2001
Externally published	Yes

Keywords

Bipolar disorder
Body mass index
Diabetes mellitus
Topiramate
Weight loss

ASJC Scopus subject areas

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0924-9338(01)00562-4

Cite this

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keywords = "Bipolar disorder, Body mass index, Diabetes mellitus, Topiramate, Weight loss",

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AU - Levine, J.

AU - Rathore, D.

AU - Parepally, H.

AU - Atzert, R.

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AB - Topiramate is an antiepileptic agent, which is being investigated as a mood-stabilizer. Three obese individuals with DSM-IV bipolar I disorder and type II diabetes mellitus received topiramate treatment in combination with antipsychotics and valproate or carbamazepine. In addition to improved mood stability, these individuals lost between 16 to 20.5% of their pre-topiramate body weight and also achieved significant glycemic control.

KW - Bipolar disorder

KW - Body mass index

KW - Diabetes mellitus

KW - Topiramate

KW - Weight loss

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JO - European Psychiatry

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IS - 3

ER -

Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: A case-series

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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