Long-term follow-up after leptospirosis

Ofer Shpilberg, Yechiel Shared, Michael K. Maier, Drora Samra, Yecheskel Samra

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Human leptospirosis is an infectious disease that is a substantial problem in the Third World, but it can occur in developed countries as well. Survivors of the acute disease are considered to recover without sequelae, though little literature exists on long-term follow-up among these patients. Eleven patients, at an average of 22 years after acute leptospirosis, were reevaluated for possible delayed sequelae. Results showed that liver and renal disease had resolved, but headache and ophthalmic sequelae persisted. Even though the number of patients involved in this study is small, it appears that the eyes, particularly the anterior chambers, may be the site of continuing morbidity after acute human leptospirosis. The pathogenesis for persistent headache is not known.

Original languageEnglish
Pages (from-to)405-407
Number of pages3
JournalSouthern Medical Journal
Issue number4
StatePublished - 1 Jan 1990
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)


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