Long term outcomes of MGuard stent deployment in saphenous vein grafts and native coronary arteries: A single center experience

Hana Vaknin-Assa, Abid Assali, Eli I. Lev, Gabriel Greenberg, Katia Orvin, Orna Valzer, Gideon Paul, Amos Levi, Ran Kornowski

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Background: The MGuard™ stent (InspireMD, Tel Aviv, Israel) is a bare metal mesh-covered stent, developed to prevent no-reflow phenomenon during percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) and acute myocardial infarction (MI), both associated with significant atherothrombotic lesions. Objective: To report on local experience with patients treated with the MGuard stent until follow-up at 1 year. Methods: We followed 163 consecutive patients who underwent MGuard stent deployment during the period 2009 to 2014 in a large tertiary cardiac center in central Israel. Results: The MGuard stent was used in 67% of patients who underwent SVG-PCI while 33% were treated for native coronary artery disease, the majority during ST-elevation MI (STEMI). The mean age was 67 years and 83% were males. The clinical presentation was STEMI in 35% and non-STEMI/unstable angina in 58% of patients. Of the total number of patients, 47% had diabetes and 29% had chronic kidney disease. All patients had follow-up at 1 year. Mortality in the native group was 1.9% vs. 10% in the vein graft cohort. ST was 2% in both groups. The major adverse cardiac event (MACE) rates were 11% in the native artery and 29% in the vein graft group, mainly due to respective target lesion revascularization/target vessel revascularization rates of 6% and 7% in the native vessel group and 11% and 15% in the SVG group. Conclusions: In suitable patients undergoing SVG-PCI or native lesion intervention during acute MI, the MGuard stent is a viable treatment strategy. Its potential merits and limitations warrant further evaluation.

Original languageEnglish
Pages (from-to)172-176
Number of pages5
JournalIsrael Medical Association Journal
Volume19
Issue number3
StatePublished - 1 Mar 2017
Externally publishedYes

Keywords

  • MGuard stent
  • Percutaneous coronary intervention (PCI)
  • ST-elevation MI (STEMI)
  • Vein grafts

ASJC Scopus subject areas

  • Medicine (all)

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