TY - JOUR
T1 - Long-term prognosis after acute myocardial infarction in patients with left ventricular hypertrophy on the electrocardiogram
AU - Behar, Solomon
AU - Reicher-Reiss, Henrietta
AU - Abinader, Edward
AU - Agmon, Jacob
AU - Barzilai, Jacob
AU - Friedman, Yaacov
AU - Kaplinsky, Elieser
AU - Kauli, Nissim
AU - Kishon, Yehezkiel
AU - Palant, Abraham
AU - Peled, Benyamin
AU - Reisin, Leonardo
AU - Schlesinger, Zwi
AU - Zahavi, Izhar
AU - Zion, Monty
AU - Goldbourt, Uri
N1 - Funding Information:
From the Neufeld Cardiac Research Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel. The collection of the SPRINT Registry data was supported by a research grant from Sayer AG, Wuppertal, Germany, within the framework of the SPRINT Study. Manuscript received May 9, 1991; revised manuscript received and accepted December 18,199l.
PY - 1992/4/15
Y1 - 1992/4/15
N2 - Among 4,720 consecutive hospital survivors from acute myocardial infarction (AMI) treated in 13 coronary care units between July 1981 and August 1983, the estimated prevalence of electrocardiographic left ventricular (LV) hypertrophy was 6.1%. The prevalence of electrocardiographs LV hypertrophy increased with age and was higher in patients with previous myocardial infarction, angina and systemic hypertension. Mean age of patients with electrocardiographic LV hypertrophy was 67.2 vs 61.4 years in counterparts free of electrocardiographic LV hypertrophy. Patients with electrocardiographic LV hypertrophy had a higher rate of congestive heart failure on admission, or developing during their stay in coronary care units. The 1- and 5-year mortality rates were 19.7 and 46.6% among patients with electrocardiographic LV hypertrophy versus 8.7 and 26.2%, respectively (p <0.001) in patients without this finding. The covariate-adjusted odds ratio of 1-year mortality was 1.88 for the presence of electrocardiographic LV hypertrophy when age alone was adjusted for, and 1.51 (90% confidence interval, 1.09 to 2.10) when multiple covariate adjustment was undertaken. After multiple covariate adjustment for 5-year mortality after discharge, the relative risk associated with electrocardiographic LV hypertrophy was 1.51 (90% confidence interval, 1.26 to 1.80). The results of the present study showed that the presence of electrocardiographic LV hypertrophy on the discharge electrocardiogram of survivors from AMI is associated with a 1.5-fold increase of short- and long-term mortality. Patients with electrocardiographic LV hypertrophy, potentially at an increased post-discharge risk, may be candidates for early noninvasive testing and more intensive follow-up after recovering from AMI.
AB - Among 4,720 consecutive hospital survivors from acute myocardial infarction (AMI) treated in 13 coronary care units between July 1981 and August 1983, the estimated prevalence of electrocardiographic left ventricular (LV) hypertrophy was 6.1%. The prevalence of electrocardiographs LV hypertrophy increased with age and was higher in patients with previous myocardial infarction, angina and systemic hypertension. Mean age of patients with electrocardiographic LV hypertrophy was 67.2 vs 61.4 years in counterparts free of electrocardiographic LV hypertrophy. Patients with electrocardiographic LV hypertrophy had a higher rate of congestive heart failure on admission, or developing during their stay in coronary care units. The 1- and 5-year mortality rates were 19.7 and 46.6% among patients with electrocardiographic LV hypertrophy versus 8.7 and 26.2%, respectively (p <0.001) in patients without this finding. The covariate-adjusted odds ratio of 1-year mortality was 1.88 for the presence of electrocardiographic LV hypertrophy when age alone was adjusted for, and 1.51 (90% confidence interval, 1.09 to 2.10) when multiple covariate adjustment was undertaken. After multiple covariate adjustment for 5-year mortality after discharge, the relative risk associated with electrocardiographic LV hypertrophy was 1.51 (90% confidence interval, 1.26 to 1.80). The results of the present study showed that the presence of electrocardiographic LV hypertrophy on the discharge electrocardiogram of survivors from AMI is associated with a 1.5-fold increase of short- and long-term mortality. Patients with electrocardiographic LV hypertrophy, potentially at an increased post-discharge risk, may be candidates for early noninvasive testing and more intensive follow-up after recovering from AMI.
UR - http://www.scopus.com/inward/record.url?scp=0027067781&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(92)90851-O
DO - 10.1016/0002-9149(92)90851-O
M3 - Article
AN - SCOPUS:0027067781
SN - 0002-9149
VL - 69
SP - 985
EP - 990
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 12
ER -