Low CSF soluble interleukin 2 receptor levels in acute depression

J. Levine, Y. Barak, K. R.N. Chengappa, A. Rapoport, S. M. Antelman, V. Barak

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations


    Thirteen patients with DSM-III-R diagnosis of either major depression or bipolar I depression participated in the study. The control group consisted of 10 subjects evaluated for headache or suspected meningitis, none of whom were found to suffer from any organic disease. CSF was withdrawn from all subjects for the measurement of soluble interleukin 2 receptor (sIL-2R). CSF sIL-2R levels were found to be lower in patients as compared to controls (df = 1, 20; F = 84; p < 0.000001).

    Original languageEnglish
    Pages (from-to)1011-1015
    Number of pages5
    JournalJournal of Neural Transmission
    Issue number9-10
    StatePublished - 17 Nov 1999


    • Cerebrospinal fluid
    • Major depression
    • Soluble interleukin-2 receptor

    ASJC Scopus subject areas

    • Neurology
    • Clinical Neurology
    • Psychiatry and Mental health
    • Biological Psychiatry


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