Low-molecular-weight heparin for prosthetic heart valves: Treatment failure

Oren Lev-Ran, Amir Kramer, Jacob Gurevitch, Itzhak Shapira, Rephael Mohr

Research output: Contribution to journalArticlepeer-review

110 Scopus citations


There is no adequate substitute therapy for patients with prosthetic heart valves, in whom anticoagulation with warfarin or unfractionated heparin must be withheld. In the literature there are several reports describing successful treatment with low-molecular-weight heparin in patients with prosthetic heart valves. We report two cases of low-molecular-weight heparin treatment failure resulting in thrombosed prosthetic heart valves with stormy clinical presentations, who underwent successful valve replacements. (C) 2000 by The Society of Thoracic Surgeons.

Original languageEnglish
Pages (from-to)264-265
Number of pages2
JournalAnnals of Thoracic Surgery
Issue number1
StatePublished - 1 Jan 2000
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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