Lymphocyte response to a bovine milk protein in ulcerative colitis

J. Faber, S. Zaides, O. Kuperman, W. Z. Jacobsohn, S. Weil, S. Freier

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A recently described in vitro test for cow's milk protein hypersensitivity was applied to adult patients with ulcerative colitis. The test system involved the culture of their peripheral blood lymphocytes with and without β-lactoglobulin, and the results were expressed as a stimulation index. Stimulation with β-lactoglobulin was significantly higher (P < 0.02) in patients with active disease than in those with inactive disease or in healthy controls. β-Lactoglobulin was the only one of four cow's milk proteins that showed this effect. It is concluded that the cow's milk protein β-lactoglobulin has a specific blastogenic effect on the lymphocytes of patients with active ulcerative colitis, and. therefore, may serve as a marker of disease activity.

Original languageEnglish
Pages (from-to)575-578
Number of pages4
JournalIsrael Journal of Medical Sciences
Issue number7
StatePublished - 1 Dec 1985
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering


Dive into the research topics of 'Lymphocyte response to a bovine milk protein in ulcerative colitis'. Together they form a unique fingerprint.

Cite this