Lymphoplasmacytic lymphoma and multiple myeloma coexisting in the same patient: a case series and literature review

Gilad Itchaki, Osnat Jarhovsky, Jorge J. Castillo, Hamza Hassan, Moshe L. Gatt, Merav Leiba, Pia Raanani, Morie A. Gertz, Iuliana Vaxman

Research output: Contribution to journalArticlepeer-review

Abstract

The simultaneous occurrence of Waldenström macroglobulinemia and multiple myeloma in the same patient has been published as case reports. Patients with Waldenström macroglobulinemia often have a small clone of plasma cells. However, the concurrent occurrence of symptomatic myeloma with lytic bone lesions is rare. The diagnosis of this ‘hybrid’ entity is challenging, and there are no standard therapies. We present six patients from five centers (three in Israel and two in the United States). We describe these patients’ unique clinical course and treatment approaches.

Original languageEnglish
JournalLeukemia and Lymphoma
DOIs
StateAccepted/In press - 1 Jan 2024
Externally publishedYes

Keywords

  • Myeloma
  • Waldenström macroglobulinemia
  • plasma cell dyscrasia

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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