Lymphoplasmacytic lymphoma and multiple myeloma coexisting in the same patient: a case series and literature review

Gilad Itchaki; Osnat Jarhovsky; Jorge J. Castillo; Hamza Hassan; Moshe L. Gatt; Merav Leiba; Pia Raanani; Morie A. Gertz; Iuliana Vaxman

doi:10.1080/10428194.2024.2332499

Lymphoplasmacytic lymphoma and multiple myeloma coexisting in the same patient: a case series and literature review

Gilad Itchaki, Osnat Jarhovsky, Jorge J. Castillo, Hamza Hassan, Moshe L. Gatt, Merav Leiba, Pia Raanani, Morie A. Gertz, Iuliana Vaxman

Research output: Contribution to journal › Article › peer-review

Abstract

The simultaneous occurrence of Waldenström macroglobulinemia and multiple myeloma in the same patient has been published as case reports. Patients with Waldenström macroglobulinemia often have a small clone of plasma cells. However, the concurrent occurrence of symptomatic myeloma with lytic bone lesions is rare. The diagnosis of this ‘hybrid’ entity is challenging, and there are no standard therapies. We present six patients from five centers (three in Israel and two in the United States). We describe these patients’ unique clinical course and treatment approaches.

Original language	English
Pages (from-to)	943-949
Number of pages	7
Journal	Leukemia and Lymphoma
Volume	65
Issue number	7
DOIs	https://doi.org/10.1080/10428194.2024.2332499
State	Published - 1 Jan 2024

Keywords

Myeloma
Waldenström macroglobulinemia
plasma cell dyscrasia

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/10428194.2024.2332499

Cite this

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title = "Lymphoplasmacytic lymphoma and multiple myeloma coexisting in the same patient: a case series and literature review",

abstract = "The simultaneous occurrence of Waldenstr{\"o}m macroglobulinemia and multiple myeloma in the same patient has been published as case reports. Patients with Waldenstr{\"o}m macroglobulinemia often have a small clone of plasma cells. However, the concurrent occurrence of symptomatic myeloma with lytic bone lesions is rare. The diagnosis of this {\textquoteleft}hybrid{\textquoteright} entity is challenging, and there are no standard therapies. We present six patients from five centers (three in Israel and two in the United States). We describe these patients{\textquoteright} unique clinical course and treatment approaches.",

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AU - Itchaki, Gilad

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AU - Castillo, Jorge J.

AU - Hassan, Hamza

AU - Gatt, Moshe L.

AU - Leiba, Merav

AU - Raanani, Pia

AU - Gertz, Morie A.

AU - Vaxman, Iuliana

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N2 - The simultaneous occurrence of Waldenström macroglobulinemia and multiple myeloma in the same patient has been published as case reports. Patients with Waldenström macroglobulinemia often have a small clone of plasma cells. However, the concurrent occurrence of symptomatic myeloma with lytic bone lesions is rare. The diagnosis of this ‘hybrid’ entity is challenging, and there are no standard therapies. We present six patients from five centers (three in Israel and two in the United States). We describe these patients’ unique clinical course and treatment approaches.

AB - The simultaneous occurrence of Waldenström macroglobulinemia and multiple myeloma in the same patient has been published as case reports. Patients with Waldenström macroglobulinemia often have a small clone of plasma cells. However, the concurrent occurrence of symptomatic myeloma with lytic bone lesions is rare. The diagnosis of this ‘hybrid’ entity is challenging, and there are no standard therapies. We present six patients from five centers (three in Israel and two in the United States). We describe these patients’ unique clinical course and treatment approaches.

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KW - Waldenström macroglobulinemia

KW - plasma cell dyscrasia

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Lymphoplasmacytic lymphoma and multiple myeloma coexisting in the same patient: a case series and literature review

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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