Malignant Melanoma in Association with a Thymic Nevus in a Patient with a Giant Congenital Nevus

Yulia Shvartser-Beryozkin, Alexander Yakobson, Daniel Benharroch, Milton Saute, Meora Feinmesser

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations

    Abstract

    Nevi and melanocytic proliferations are known to appear in multiple extracutaneous sites, including lymph nodes and meninges. We report a case of an anterior mediastinal mass in a patient with a giant congenital nevus and neurofibromatosis type I. Histologically, the tumor was found to be a malignant melanoma in the thymus arising in association with a nevus that involved most of the thymic tissue. There was no sign of cutaneous melanoma on skin examination. We suggest that the tumor originated from the benign nevus in the thymus, a rare extracutaneous location for nevi and malignant melanoma.

    Original languageEnglish
    Pages (from-to)538-541
    Number of pages4
    JournalAmerican Journal of Dermatopathology
    Volume39
    Issue number7
    DOIs
    StatePublished - 1 Jul 2017

    Keywords

    • extracutaneous nevus
    • giant pigmented nevus
    • malignant melanoma
    • thymus

    ASJC Scopus subject areas

    • Pathology and Forensic Medicine
    • Dermatology

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