Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma

Shlomi Codish; Mahmoud Abu-Shakra; Samuel Ariad; Howard J. Zirkin; Tikva Yermiyahu; Nicolas Dupin; Chris Boshoff; Shaul Sukenik

doi:10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma

Shlomi Codish, Mahmoud Abu-Shakra, Samuel Ariad, Howard J. Zirkin, Tikva Yermiyahu, Nicolas Dupin, Chris Boshoff, Shaul Sukenik

Faculty of Health Sciences

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

We describe a 73-year-old HIV negative patient who presented with symptomatic hypoglycemia. Over the course of several months she was diagnosed with three human herpesvirus-8 related diseases: multicentric Castleman's disease, primary effusion lymphoma and Kaposi's sarcoma. No improvement was observed following cytotoxic therapy and she died 16 months after her initial presentation. The etiology of the hypoglycemia remained obscure over the course of this patient's disease. This case is the first report of a patient with three human herpesvirus-8 related diseases, and the first report of severe hypoglycemia as the presenting symptom of any of these diseases. (C) 2000 Wiley-Liss, Inc.

Original language	English
Pages (from-to)	310-314
Number of pages	5
Journal	American Journal of Hematology
Volume	65
Issue number	4
DOIs	https://doi.org/10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G
State	Published - 29 Nov 2000

Keywords

Castleman's disease
Hypoglycemia
Kaposi's sarcoma
Kaposi's sarcoma-associated herpesvirus
Primary effusion lymphoma

ASJC Scopus subject areas

Hematology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

Cite this

Codish, S., Abu-Shakra, M., Ariad, S., Zirkin, H. J., Yermiyahu, T., Dupin, N., Boshoff, C., & Sukenik, S. (2000). Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma. American Journal of Hematology, 65(4), 310-314. https://doi.org/10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

@article{98502e269f0f4a1ea6240a931a3688f8,

title = "Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma",

abstract = "We describe a 73-year-old HIV negative patient who presented with symptomatic hypoglycemia. Over the course of several months she was diagnosed with three human herpesvirus-8 related diseases: multicentric Castleman's disease, primary effusion lymphoma and Kaposi's sarcoma. No improvement was observed following cytotoxic therapy and she died 16 months after her initial presentation. The etiology of the hypoglycemia remained obscure over the course of this patient's disease. This case is the first report of a patient with three human herpesvirus-8 related diseases, and the first report of severe hypoglycemia as the presenting symptom of any of these diseases. (C) 2000 Wiley-Liss, Inc.",

keywords = "Castleman's disease, Hypoglycemia, Kaposi's sarcoma, Kaposi's sarcoma-associated herpesvirus, Primary effusion lymphoma",

author = "Shlomi Codish and Mahmoud Abu-Shakra and Samuel Ariad and Zirkin, {Howard J.} and Tikva Yermiyahu and Nicolas Dupin and Chris Boshoff and Shaul Sukenik",

year = "2000",

month = nov,

day = "29",

doi = "10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G",

language = "English",

volume = "65",

pages = "310--314",

journal = "American Journal of Hematology",

issn = "0361-8609",

publisher = "John Wiley and Sons Inc.",

number = "4",

}

Codish, S, Abu-Shakra, M, Ariad, S, Zirkin, HJ, Yermiyahu, T, Dupin, N, Boshoff, C & Sukenik, S 2000, 'Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma', American Journal of Hematology, vol. 65, no. 4, pp. 310-314. https://doi.org/10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma. / Codish, Shlomi; Abu-Shakra, Mahmoud; Ariad, Samuel et al.
In: American Journal of Hematology, Vol. 65, No. 4, 29.11.2000, p. 310-314.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Manifestations of three HHV-8-related diseases in an HIV-negative patient

T2 - Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma

AU - Codish, Shlomi

AU - Abu-Shakra, Mahmoud

AU - Ariad, Samuel

AU - Zirkin, Howard J.

AU - Yermiyahu, Tikva

AU - Dupin, Nicolas

AU - Boshoff, Chris

AU - Sukenik, Shaul

PY - 2000/11/29

Y1 - 2000/11/29

N2 - We describe a 73-year-old HIV negative patient who presented with symptomatic hypoglycemia. Over the course of several months she was diagnosed with three human herpesvirus-8 related diseases: multicentric Castleman's disease, primary effusion lymphoma and Kaposi's sarcoma. No improvement was observed following cytotoxic therapy and she died 16 months after her initial presentation. The etiology of the hypoglycemia remained obscure over the course of this patient's disease. This case is the first report of a patient with three human herpesvirus-8 related diseases, and the first report of severe hypoglycemia as the presenting symptom of any of these diseases. (C) 2000 Wiley-Liss, Inc.

AB - We describe a 73-year-old HIV negative patient who presented with symptomatic hypoglycemia. Over the course of several months she was diagnosed with three human herpesvirus-8 related diseases: multicentric Castleman's disease, primary effusion lymphoma and Kaposi's sarcoma. No improvement was observed following cytotoxic therapy and she died 16 months after her initial presentation. The etiology of the hypoglycemia remained obscure over the course of this patient's disease. This case is the first report of a patient with three human herpesvirus-8 related diseases, and the first report of severe hypoglycemia as the presenting symptom of any of these diseases. (C) 2000 Wiley-Liss, Inc.

KW - Castleman's disease

KW - Hypoglycemia

KW - Kaposi's sarcoma

KW - Kaposi's sarcoma-associated herpesvirus

KW - Primary effusion lymphoma

UR - http://www.scopus.com/inward/record.url?scp=0033739853&partnerID=8YFLogxK

U2 - 10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

DO - 10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

M3 - Article

C2 - 11074561

AN - SCOPUS:0033739853

SN - 0361-8609

VL - 65

SP - 310

EP - 314

JO - American Journal of Hematology

JF - American Journal of Hematology

IS - 4

ER -

Codish S, Abu-Shakra M, Ariad S, Zirkin HJ, Yermiyahu T, Dupin N et al. Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma. American Journal of Hematology. 2000 Nov 29;65(4):310-314. doi: 10.1002/1096-8652(200012)65:4<310::AID-AJH11>3.0.CO;2-G

Manifestations of three HHV-8-related diseases in an HIV-negative patient: Immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this