Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan

Maximo Maislos; Naif Khamaysi; Abid Assali; Yunes Abou-Rabiah; Irenne Zvili; Shraga Shany

doi:10.1093/ajcn/57.5.640

Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan

Maximo Maislos, Naif Khamaysi, Abid Assali, Yunes Abou-Rabiah, Irenne Zvili, Shraga Shany

Basic Sciences Divisions

Research output: Contribution to journal › Article › peer-review

120 Scopus citations

Abstract

We evaluated the effect of the Ramadan fasting on plasma lipids and lipoproteins in normal individuals. Twenty-four healthy subjects were studied before the end of the Ramadan month (Ram) and for 1 mo thereafter. Plasma total cholesterol (TC), triglycerides, low-density-lipoprotein cholesterol (LDL-C), and very-low-density-lipoprotein cholesterol (VLDL-C) did not change. High-density-lipoprotein cholesterol (HDL-C) was 30% higher (P < 0.005) at the end of Ram; apolipoprotein A-I also increased (P < 0.0001). Both the ratios of TC to HDL-C and LDL-C to HDL-C (P < 0.001) decreased at Ram. There was a striking nonpharmacologic improvement in plasma HDL-C and ratios of TC to HDL-C and LDL-C to HDL-C, which were most probably induced by eating one large evening meal a day. Further studies to determine the mechanism of this observation are underway.

Original language	English
Pages (from-to)	640-642
Number of pages	3
Journal	American Journal of Clinical Nutrition
Volume	57
Issue number	5
DOIs	https://doi.org/10.1093/ajcn/57.5.640
State	Published - 1 Jan 1993

Keywords

Cholesterol
Fasting
Gorging
High-density-lipoprotein cholesterol
Lipoproteins
Nibbling
Ramadan

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics

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10.1093/ajcn/57.5.640

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title = "Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan",

abstract = "We evaluated the effect of the Ramadan fasting on plasma lipids and lipoproteins in normal individuals. Twenty-four healthy subjects were studied before the end of the Ramadan month (Ram) and for 1 mo thereafter. Plasma total cholesterol (TC), triglycerides, low-density-lipoprotein cholesterol (LDL-C), and very-low-density-lipoprotein cholesterol (VLDL-C) did not change. High-density-lipoprotein cholesterol (HDL-C) was 30\% higher (P < 0.005) at the end of Ram; apolipoprotein A-I also increased (P < 0.0001). Both the ratios of TC to HDL-C and LDL-C to HDL-C (P < 0.001) decreased at Ram. There was a striking nonpharmacologic improvement in plasma HDL-C and ratios of TC to HDL-C and LDL-C to HDL-C, which were most probably induced by eating one large evening meal a day. Further studies to determine the mechanism of this observation are underway.",

keywords = "Cholesterol, Fasting, Gorging, High-density-lipoprotein cholesterol, Lipoproteins, Nibbling, Ramadan",

author = "Maximo Maislos and Naif Khamaysi and Abid Assali and Yunes Abou-Rabiah and Irenne Zvili and Shraga Shany",

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T1 - Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan

AU - Maislos, Maximo

AU - Khamaysi, Naif

AU - Assali, Abid

AU - Abou-Rabiah, Yunes

AU - Zvili, Irenne

AU - Shany, Shraga

PY - 1993/1/1

Y1 - 1993/1/1

N2 - We evaluated the effect of the Ramadan fasting on plasma lipids and lipoproteins in normal individuals. Twenty-four healthy subjects were studied before the end of the Ramadan month (Ram) and for 1 mo thereafter. Plasma total cholesterol (TC), triglycerides, low-density-lipoprotein cholesterol (LDL-C), and very-low-density-lipoprotein cholesterol (VLDL-C) did not change. High-density-lipoprotein cholesterol (HDL-C) was 30% higher (P < 0.005) at the end of Ram; apolipoprotein A-I also increased (P < 0.0001). Both the ratios of TC to HDL-C and LDL-C to HDL-C (P < 0.001) decreased at Ram. There was a striking nonpharmacologic improvement in plasma HDL-C and ratios of TC to HDL-C and LDL-C to HDL-C, which were most probably induced by eating one large evening meal a day. Further studies to determine the mechanism of this observation are underway.

AB - We evaluated the effect of the Ramadan fasting on plasma lipids and lipoproteins in normal individuals. Twenty-four healthy subjects were studied before the end of the Ramadan month (Ram) and for 1 mo thereafter. Plasma total cholesterol (TC), triglycerides, low-density-lipoprotein cholesterol (LDL-C), and very-low-density-lipoprotein cholesterol (VLDL-C) did not change. High-density-lipoprotein cholesterol (HDL-C) was 30% higher (P < 0.005) at the end of Ram; apolipoprotein A-I also increased (P < 0.0001). Both the ratios of TC to HDL-C and LDL-C to HDL-C (P < 0.001) decreased at Ram. There was a striking nonpharmacologic improvement in plasma HDL-C and ratios of TC to HDL-C and LDL-C to HDL-C, which were most probably induced by eating one large evening meal a day. Further studies to determine the mechanism of this observation are underway.

KW - Cholesterol

KW - Fasting

KW - Gorging

KW - High-density-lipoprotein cholesterol

KW - Lipoproteins

KW - Nibbling

KW - Ramadan

UR - https://www.scopus.com/pages/publications/0027300920

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DO - 10.1093/ajcn/57.5.640

M3 - Article

AN - SCOPUS:0027300920

SN - 0002-9165

VL - 57

SP - 640

EP - 642

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

IS - 5

ER -

Marked increase in plasma high-density-lipoprotein cholesterol after prolonged fasting during Ramadan

Abstract

Keywords

ASJC Scopus subject areas

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