Maternal thrombophilia and adverse pregnancy outcomes

Adi Y. Weintraub, Fernanda Press, Arnon Wiznitzer, Eyal Sheiner

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations

    Abstract

    Thrombophilias are inherited or acquired conditions that predispose an individual to thromboembolism. During pregnancy, maternal thrombophilia has been identified as a major risk factor for adverse pregnancy outcomes (APO), including venous and arterial thrombosis, preeclampsia, placental abruption, intrauterine growth restriction, intrauterine fetal losses and recurrent miscarriages. Although a great body of evidence has accumulated regarding this association, there is still much controversy. In this review, aspects of certain APO and thrombophilia are discussed, as well as prophylactic and therapeutic implications.

    Original languageEnglish
    Pages (from-to)203-216
    Number of pages14
    JournalExpert Review of Obstetrics and Gynecology
    Volume2
    Issue number2
    DOIs
    StatePublished - 1 Mar 2007

    Keywords

    • adverse pregnancy outcomes
    • antiphospholipid syndrome
    • low-molecular-weight heparin
    • thrombophilia

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