Matrix metalloproteinase-7 activation of mouse paneth cell pro-α-defensins: SER43 ↓ ILE44 proteolysis enables membrane-disruptive activity

Colby S. Weeks, Hiroki Tanabe, Jason E. Cummings, Steve P. Crampton, Tanya Sheynis, Raz Jelinek, T. Kyle Vanderlick, Melanie J. Cocco, Andre J. Ouellette

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology