Abstract
Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of cancer stem cell differentiation and reduction of TAMs abundance and tumor angiogenesis, thereby preventing tumor invention and recurrence.
| Original language | English |
|---|---|
| Patent number | US2018327753 |
| IPC | A61P 35/ 00 A I |
| Priority date | 10/11/16 |
| State | Published - 15 Nov 2018 |
