Abstract
Provided are RNA inhibitory molecules, particularly siRNA molecules silencing the expression of Voltage-Dependent Ion Chanel-1 (VDAC1) for the induction of cancer stem cell differentiation and reduction of TAMs abundance and tumor angiogenesis, thereby preventing tumor invention and recurrence.
| Original language | English |
|---|---|
| Patent number | HK1258902 |
| IPC | C12Q C I |
| Priority date | 10/11/16 |
| State | Published - 22 Nov 2019 |