Measuring inter-protein pairwise interaction energies from a single native mass spectrum by double-mutant cycle analysis

Biochemistry, Genetics and Molecular Biology

• Amino Acids 50%
• Binding Affinity 50%
• Complex Formation 50%
• Energy Transfer 50%
• Magnetism 50%
• Mass Spectrometry 50%
• Mass Spectrum 100%
• Mutant Protein 100%
• Protein Complexes 50%
• Solution and Solubility 50%
• Wild Type 100%

Chemistry

• Amino Acid 50%
• Energetics 50%
• Kd 50%
• Mass Spectrometry 50%
• Mass Spectrum 100%
• NMR Spectroscopy 50%
• Nuclear Overhauser Effect 50%

Keyphrases

• Inter-protein Contact 50%
• Native Mass Spectrometry 50%
• Pair Interaction Energy 100%
• Protein Complex Formation 50%