MECHANICAL AND FUNCTIONAL EFFECTS OF ISCHEMIC STATES IN THE LEFT VENTRICLE.

A. Horowitz, M. Perl

Research output: Contribution to conferencePaperpeer-review

Abstract

Several ischemic states including infarction, affecting regions of varying sizes in a canine left ventricle (LV) are simulated by a mechanical finite element model. The simulation examines the effect of an immediate partial or full degradation of the contractility of the damaged region occurring at the onset of the ejection phase, while the passive mechanical properties of this region are yet unaltered. The results show a progressive decrease in the ejection fraction (EF) which is directly related to both ischemia level and ischemic region size, up to a reduction in EF of 33% for an infarct affecting 43% of the LV wall volume. The infarction induces also significant alternations in the deformation and stress patterns of the LV.

Original languageEnglish
Pages48-50
Number of pages3
StatePublished - 1 Dec 1986
Externally publishedYes

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