Medical Cannabis Is Not Associated with a Decrease in Activities of Daily Living in Older Adults

Ran Abuhasira, Lihi Schwartz, Victor Novack

    Research output: Contribution to journalArticlepeer-review


    The proportion of older adults using medical cannabis is rising. Therefore, we aimed to assess the effects of herbal medical cannabis on the functional status of older adults. We conducted a prospective observational study of patients aged 65 years or older that initiated cannabis treatment for different indications, mostly chronic non-cancer pain, during 2018–2020 in a specialized geriatric clinic. The outcomes assessed were activities of daily living (ADL), instrumental activities of daily living (IADL), pain intensity, geriatric depression scale, chronic medication use, and adverse events at six months. A cohort of 119 patients began cannabis treatment: the mean age was 79.3 ± 8.5 and 74 (62.2%) were female. Of the cohort, 43 (36.1%) experienced adverse effects due to cannabis use and 2 (1.7%) required medical attention. The mean ADL scores before and after treatment were 4.4 ± 1.8 and 4.5 ± 1.8, respectively (p = 0.27), and the mean IADL scores before and after treatment were 4.1 ± 2.6 and 4.7 ± 3, respectively (p = 0.02). We concluded that medical cannabis in older adults has a number of serious adverse events, but was not associated with a decrease in functional status, as illustrated by ADL and IADL scores after six months of continuous treatment.

    Original languageEnglish
    Article number2697
    Issue number10
    StatePublished - 1 Oct 2023


    • functional status
    • marijuana
    • medical cannabis
    • older adults
    • opioids

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • General Biochemistry, Genetics and Molecular Biology


    Dive into the research topics of 'Medical Cannabis Is Not Associated with a Decrease in Activities of Daily Living in Older Adults'. Together they form a unique fingerprint.

    Cite this