Medicinal properties of lilium candidum l. And its phytochemicals

Michele Zaccai, Ludmila Yarmolinsky, Boris Khalfin, Arie Budovsky, Jonathan Gorelick, Arik Dahan, Shimon Ben-Shabat

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Lilium candidum L., known as Madonna, meadow, or white lily, is a bulbous plant from the Liliaceae family, originating in the Middle East. L. candidum has been abundantly used in folk medicine since ancient times to relieve a variety of ailments, including age-related diseases, burns, ulcers, and coughs. The aim of this article is to investigate the anti-inflammatory and anti-diabetic activities of L. candidum extracts and its active phytochemicals. Some active volatile phytochemicals were identified using gas chromatography–mass spectrometry (GC-MS) analysis. Significant (p < 0.001) anti-diabetic properties of the extracts kaempferol, linalool, citronellal, and humulene were demonstrated by an elevation in glucose uptake by adipocytes. The significant (p < 0.01) effect of the plant extracts kaempferol, citronellal, and humulene on the secretion of pro-inflammatory cytokines interleukin 6 (IL-6) and interleukin 8 (IL-8) was demonstrated using enzyme-linked immunosorbent assay. Altogether, L. candidum and its rich collection of phytochemicals hold promising medicinal potential, and further investigations of its therapeutic prospects are encouraged.

Original languageEnglish
Article number959
Pages (from-to)1-11
Number of pages11
Issue number8
StatePublished - 1 Aug 2020


  • Lilium candidum
  • Medicinal activities
  • Phytochemicals

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science


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