Melatonin replacement corrects sleep disturbances in a child with pineal tumor

A. Etzioni, R. Luboshitzky, D. Tiosano, M. Ben-Harush, D. Goldsher, P. Lavie

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

A child with a germ cell tumor involving the pineal region had marked suppressed melatonin secretion associated with severe insomnia. Exogenous melatonin (3 mg in the evening) for 2 weeks restored sleep continuity, as demonstrated by objective monitoring of rest-activity cycles. This case report provides direct evidence of the essential role of melatonin in normal sleep.

Original languageEnglish
Pages (from-to)261-263
Number of pages3
JournalNeurology
Volume46
Issue number1
DOIs
StatePublished - 1 Jan 1996
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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