Abstract
A child with a germ cell tumor involving the pineal region had marked suppressed melatonin secretion associated with severe insomnia. Exogenous melatonin (3 mg in the evening) for 2 weeks restored sleep continuity, as demonstrated by objective monitoring of rest-activity cycles. This case report provides direct evidence of the essential role of melatonin in normal sleep.
Original language | English |
---|---|
Pages (from-to) | 261-263 |
Number of pages | 3 |
Journal | Neurology |
Volume | 46 |
Issue number | 1 |
DOIs | |
State | Published - 1 Jan 1996 |
Externally published | Yes |
ASJC Scopus subject areas
- Clinical Neurology