Membrane heterogeneity created by transertion is a global regulator in bacteria

Itzhak Fishov, Vic Norris

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


The bacterial membrane is characterized by a heterogeneous distribution of lipids and proteins and of higher level structures termed hyperstructures. The causes of this heterogeneity include lipid-lipid, protein-protein and protein-lipid interactions. The coupling of transcription, translation and insertion of nascent proteins into membrane, transertion, creates large membrane domains that are proposed to be important in the regulation and execution of the cell cycle and in other functions. In describing membrane heterogeneity, we suggest here that transertion is a global regulator coupling metabolism to the cell cycle.

Original languageEnglish
Pages (from-to)724-730
Number of pages7
JournalCurrent Opinion in Microbiology
Issue number6
StatePublished - 1 Dec 2012

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases


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