Mesoporous polyphosphamide catalyzed heterogeneous one-pot Wittig olefination

Anup Mahata; Rassel Shaikh; Biswarup Chakraborty

doi:10.1039/d5cc04351d

Mesoporous polyphosphamide catalyzed heterogeneous one-pot Wittig olefination

Anup Mahata
, Rassel Shaikh
, Biswarup Chakraborty

Research output: Contribution to journal › Article › peer-review

Abstract

Phosphamides comprising -{P^V(O)NH}- linkages are used as ligand scaffolds to prepare pharmaceutical products, whereas their polymeric forms are employed as flame retardants. A mesoporous triazole-functionalized polyphosphamide (t-PPA) is reported herein as a heterogeneous organocatalyst for the catalytic Wittig reaction, achieving a cumulative TON of 1176 upon recycling. In situ reduction of the -{P^V(O)}- unit in t-PPA leads to one-pot catalytic olefination with a wide substrate scope and preferential E-configuration. Unlike the sensitive phosphine-based catalysts reported earlier for olefination, polyphosphamides can be used as robust analogs with a versatile scope for exploring P^V/III-mediated catalysis.

Original language	English
Pages (from-to)	16058-16061
Number of pages	4
Journal	Chemical Communications
Volume	61
Issue number	82
DOIs	https://doi.org/10.1039/d5cc04351d
State	Published - 9 Oct 2025
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Catalysis
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/d5cc04351d

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title = "Mesoporous polyphosphamide catalyzed heterogeneous one-pot Wittig olefination",

abstract = "Phosphamides comprising -\{PV(O)NH\}- linkages are used as ligand scaffolds to prepare pharmaceutical products, whereas their polymeric forms are employed as flame retardants. A mesoporous triazole-functionalized polyphosphamide (t-PPA) is reported herein as a heterogeneous organocatalyst for the catalytic Wittig reaction, achieving a cumulative TON of 1176 upon recycling. In situ reduction of the -\{PV(O)\}- unit in t-PPA leads to one-pot catalytic olefination with a wide substrate scope and preferential E-configuration. Unlike the sensitive phosphine-based catalysts reported earlier for olefination, polyphosphamides can be used as robust analogs with a versatile scope for exploring PV/III-mediated catalysis.",

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AU - Mahata, Anup

AU - Shaikh, Rassel

AU - Chakraborty, Biswarup

PY - 2025/10/9

Y1 - 2025/10/9

N2 - Phosphamides comprising -{PV(O)NH}- linkages are used as ligand scaffolds to prepare pharmaceutical products, whereas their polymeric forms are employed as flame retardants. A mesoporous triazole-functionalized polyphosphamide (t-PPA) is reported herein as a heterogeneous organocatalyst for the catalytic Wittig reaction, achieving a cumulative TON of 1176 upon recycling. In situ reduction of the -{PV(O)}- unit in t-PPA leads to one-pot catalytic olefination with a wide substrate scope and preferential E-configuration. Unlike the sensitive phosphine-based catalysts reported earlier for olefination, polyphosphamides can be used as robust analogs with a versatile scope for exploring PV/III-mediated catalysis.

AB - Phosphamides comprising -{PV(O)NH}- linkages are used as ligand scaffolds to prepare pharmaceutical products, whereas their polymeric forms are employed as flame retardants. A mesoporous triazole-functionalized polyphosphamide (t-PPA) is reported herein as a heterogeneous organocatalyst for the catalytic Wittig reaction, achieving a cumulative TON of 1176 upon recycling. In situ reduction of the -{PV(O)}- unit in t-PPA leads to one-pot catalytic olefination with a wide substrate scope and preferential E-configuration. Unlike the sensitive phosphine-based catalysts reported earlier for olefination, polyphosphamides can be used as robust analogs with a versatile scope for exploring PV/III-mediated catalysis.

UR - https://www.scopus.com/pages/publications/105018173988

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DO - 10.1039/d5cc04351d

M3 - Article

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AN - SCOPUS:105018173988

SN - 1359-7345

VL - 61

SP - 16058

EP - 16061

JO - Chemical Communications

JF - Chemical Communications

IS - 82

ER -

Mesoporous polyphosphamide catalyzed heterogeneous one-pot Wittig olefination

Abstract

ASJC Scopus subject areas

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