Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome

Giuseppe Morgante; Claudia Tosti; Raoul Orvieto; Maria C. Musacchio; Paola Piomboni; Vincenzo De Leo

doi:10.1016/j.fertnstert.2010.12.009

Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome

Giuseppe Morgante, Claudia Tosti, Raoul Orvieto, Maria C. Musacchio, Paola Piomboni, Vincenzo De Leo

Research output: Contribution to journal › Article › peer-review

67 Scopus citations

Abstract

To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics.

Original language	English
Pages (from-to)	2150-2152
Number of pages	3
Journal	Fertility and Sterility
Volume	95
Issue number	6
DOIs	https://doi.org/10.1016/j.fertnstert.2010.12.009
State	Published - 1 May 2011

Keywords

Metabolic syndrome
metformin
OTA
semen
testosterone

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Access to Document

10.1016/j.fertnstert.2010.12.009

Cite this

@article{90120edd705340f9a20eb790f13b7b06,

title = "Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome",

abstract = "To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics.",

keywords = "Metabolic syndrome, metformin, OTA, semen, testosterone",

author = "Giuseppe Morgante and Claudia Tosti and Raoul Orvieto and Musacchio, {Maria C.} and Paola Piomboni and {De Leo}, Vincenzo",

year = "2011",

month = may,

day = "1",

doi = "10.1016/j.fertnstert.2010.12.009",

language = "English",

volume = "95",

pages = "2150--2152",

journal = "Fertility and Sterility",

issn = "0015-0282",

publisher = "Elsevier Inc.",

number = "6",

}

TY - JOUR

T1 - Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome

AU - Morgante, Giuseppe

AU - Tosti, Claudia

AU - Orvieto, Raoul

AU - Musacchio, Maria C.

AU - Piomboni, Paola

AU - De Leo, Vincenzo

PY - 2011/5/1

Y1 - 2011/5/1

N2 - To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics.

AB - To examine the appropriate treatment of oligo-terato-asthenozoospermic patients with metabolic syndrome, 45 patients were treated with metformin for 6 months. The use of metformin was associated with a statistically significant reduction in insulin resistance and sex hormone-binding globulin levels, a statistically significant increase in serum androgen levels, and a consequent improvement in semen characteristics.

KW - Metabolic syndrome

KW - metformin

KW - OTA

KW - semen

KW - testosterone

UR - http://www.scopus.com/inward/record.url?scp=79954986243&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2010.12.009

DO - 10.1016/j.fertnstert.2010.12.009

M3 - Article

C2 - 21194687

AN - SCOPUS:79954986243

SN - 0015-0282

VL - 95

SP - 2150

EP - 2152

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 6

ER -

Metformin improves semen characteristics of oligo-terato-asthenozoospermic men with metabolic syndrome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this