Abstract
The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.
| Original language | English |
|---|---|
| Patent number | US20190359924A1 |
| State | Published - 1 Jun 2019 |