Methods and Compositions for Treating and Preventing Diabetes

Shulamit Levenberg; Eddy Karnieli; Eli Chaim Lewis; Margarita Beckerman; Chava Harel

Methods and Compositions for Treating and Preventing Diabetes

Shulamit Levenberg (Inventor), Eddy Karnieli (Inventor), Eli Chaim Lewis (Inventor), Margarita Beckerman (Inventor), Chava Harel (Inventor)

Department of Clinical Biochemistry and Pharmacology

Research output: Patent

Abstract

The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

Original language	English
Patent number	EP3746179
State	Published - 9 Dec 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Methods and Compositions for Treating and Preventing Diabetes",

abstract = "The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.",

author = "Shulamit Levenberg and Eddy Karnieli and Lewis, {Eli Chaim} and Margarita Beckerman and Chava Harel",

note = "US Patent App. 16/967,237; EP3746179 ",

year = "2021",

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day = "9",

language = "English",

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type = "Patent",

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TY - PAT

T1 - Methods and Compositions for Treating and Preventing Diabetes

AU - Levenberg, Shulamit

AU - Karnieli, Eddy

AU - Lewis, Eli Chaim

AU - Beckerman, Margarita

AU - Harel, Chava

N1 - US Patent App. 16/967,237

PY - 2021/12/9

Y1 - 2021/12/9

N2 - The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

AB - The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

M3 - Patent

M1 - EP3746179

PB - Google Patents

ER -

Methods and Compositions for Treating and Preventing Diabetes

Abstract

UN SDGs

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