Methods and Compositions for Treating and Preventing Diabetes

Shulamit Levenberg; Eddy Karnieli; Eli Chaim Lewis; Margarita Beckerman; Chava Harel

Methods and Compositions for Treating and Preventing Diabetes

Shulamit Levenberg (Inventor)
, Eddy Karnieli (Inventor)
, Eli Chaim Lewis (Inventor)
, Margarita Beckerman (Inventor)
, Chava Harel (Inventor)

Department of Clinical Biochemistry and Pharmacology

Research output: Patent

Abstract

The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

Original language	English
Patent number	EP3746179
State	Published - 9 Dec 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Methods and Compositions for Treating and Preventing Diabetes",

abstract = "The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.",

author = "Shulamit Levenberg and Eddy Karnieli and Lewis, \{Eli Chaim\} and Margarita Beckerman and Chava Harel",

note = "US Patent App. 16/967,237; EP3746179 ",

year = "2021",

month = dec,

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type = "Patent",

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TY - PAT

T1 - Methods and Compositions for Treating and Preventing Diabetes

AU - Levenberg, Shulamit

AU - Karnieli, Eddy

AU - Lewis, Eli Chaim

AU - Beckerman, Margarita

AU - Harel, Chava

N1 - US Patent App. 16/967,237

PY - 2021/12/9

Y1 - 2021/12/9

N2 - The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

AB - The present invention is directed to, inter alia, a scaffold-cell construct including a biocompatible polymer (e.g., poly-l-lactic acid (PLLA) and polylacticglycolicacid (PLGA)) and recombinant cells having increased GLUT4 levels and/or activity. The invention is further directed to methods for reducing glucose levels in a subject in need thereof. Also provided are methods of producing the scaffold-cell construct of the invention.

M3 - Patent

M1 - EP3746179

PB - Google Patents

ER -

Methods and Compositions for Treating and Preventing Diabetes

Abstract

UN SDGs

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