Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath; Francois Franceschi; Joerg Harm; Frank Schluenzen; Raz Zarivach; Anat Bashan; Renate Albrecht

Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath (Inventor), Francois Franceschi (Inventor), Joerg Harm (Inventor), Frank Schluenzen (Inventor), Raz Zarivach (Inventor), Anat Bashan (Inventor), Renate Albrecht (Inventor)

Department of Life Sciences

Research output: Patent

Abstract

Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

Original language	English
Patent number	US2009081697
IPC	G01N 33/ 554 A N
Priority date	2/12/08
State	Published - 26 Mar 2009

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title = "Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals",

abstract = "Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.",

author = "Ada Yonath and Francois Franceschi and Joerg Harm and Frank Schluenzen and Raz Zarivach and Anat Bashan and Renate Albrecht",

year = "2009",

month = mar,

day = "26",

language = "English",

type = "Patent",

note = "US2009081697; G01N 33/ 554 A N",

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TY - PAT

T1 - Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

AU - Yonath, Ada

AU - Franceschi, Francois

AU - Harm, Joerg

AU - Schluenzen, Frank

AU - Zarivach, Raz

AU - Bashan, Anat

AU - Albrecht, Renate

PY - 2009/3/26

Y1 - 2009/3/26

N2 - Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

AB - Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

M3 - Patent

M1 - US2009081697

ER -