Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath (Inventor), Francois Franceschi (Inventor), Joerg Harms (Inventor), Frank Schluenzen (Inventor), Raz Zarivach (Inventor), Anat Bashan (Inventor), Renate Albrecht (Inventor)

Research output: Patent

Abstract

Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, coordinates defining the 3D atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

Original languageEnglish GB
Patent numberUS2003027315
IPCG01N 33/ 554 A N
Priority date29/03/02
StatePublished - 6 Feb 2003

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