Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath; Anat Bashan; Raz Zarivach; Francois Franceschi; Frank Schluenzen; Joerg Harms; Renate Albrecht; Rita Berisio

Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath (Inventor), Anat Bashan (Inventor), Raz Zarivach (Inventor), Francois Franceschi (Inventor), Frank Schluenzen (Inventor), Joerg Harms (Inventor), Renate Albrecht (Inventor), Rita Berisio (Inventor)

Department of Life Sciences

Research output: Patent

Abstract

Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

Original language	English
Patent number	WO03026562
IPC	G01N 33/ 554 A N
Priority date	29/03/02
State	Published - 3 Apr 2003

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title = "Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals",

abstract = "Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.",

author = "Ada Yonath and Anat Bashan and Raz Zarivach and Francois Franceschi and Frank Schluenzen and Joerg Harms and Renate Albrecht and Rita Berisio",

year = "2003",

month = apr,

day = "3",

language = "English",

type = "Patent",

note = "WO03026562; G01N 33/ 554 A N",

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TY - PAT

T1 - Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

AU - Yonath, Ada

AU - Bashan, Anat

AU - Zarivach, Raz

AU - Franceschi, Francois

AU - Schluenzen, Frank

AU - Harms, Joerg

AU - Albrecht, Renate

AU - Berisio, Rita

PY - 2003/4/3

Y1 - 2003/4/3

N2 - Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

AB - Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

M3 - Patent

M1 - WO03026562

ER -