Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals

Ada Yonath (Inventor), Anat Bashan (Inventor), Raz Zarivach (Inventor), Francois Franceschi (Inventor), Frank Schluenzen (Inventor), Joerg Harms (Inventor), Renate Albrecht (Inventor), Rita Berisio (Inventor)

Research output: Patent

Abstract

Methods of growing crystals of free, antibiotic complexed, or ribosomal substrate complexed large ribosomal subunits, coordinates defining the three-dimensional atomic structure thereof and methods of utilizing such coordinates for rational design or identification of antibiotics or large ribosomal subunits having desired characteristics are disclosed.

Original languageEnglish GB
Patent numberWO03026562
IPCG01N 33/ 554 A N
Priority date29/03/02
StatePublished - 3 Apr 2003

Fingerprint

Dive into the research topics of 'Methods of growing crystals of free and antibiotic complexed large ribosomal subunits, and methods of rationally designing or identifying antibiotics using structure coordinate data derived from such crystals'. Together they form a unique fingerprint.

Cite this