Methotrexate in recurrent postpericardiotomy syndrome

Nili Zucker, Aviva Levitas, Eli Zalzstein

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The postpericardiotomy syndrome occurs in up to one-third of children undergoing cardiac surgery. Its treatment includes anti-inflammatory agents, diuresis, and drainage of effusions. Administration of steroids can have a dramatic effect, but is limited by adverse effects. Usually the syndrome lasts weeks only, and persistence beyond six months is exceptional. We describe a rare case of chronic postpericardiotomy syndrome, with recurrent pericardial effusions and steroid dependency, that was treated successfully with a low weekly dose of methotrexate.

Original languageEnglish
Pages (from-to)206-208
Number of pages3
JournalCardiology in the Young
Issue number2
StatePublished - 1 Apr 2003
Externally publishedYes


  • Pericardial disease
  • Postsurgical complication
  • Steroid dependency

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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