Mexiletine related chronic defibrillation threshold elevation: Case report and review of the literature

Eugene Crystal; I. Eli Ovsyshcher; Alan B. Wagshal; Amos Katz; Reuven Ilia

doi:10.1046/j.1460-9592.2002.00507.x

Mexiletine related chronic defibrillation threshold elevation: Case report and review of the literature

Eugene Crystal, I. Eli Ovsyshcher, Alan B. Wagshal, Amos Katz, Reuven Ilia

Faculty of Health Sciences

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Many antiarrhythmic drugs may produce a rise in defibrillation threshold. Mexiletine is a frequently used antiarrhythmic drug in patients with an implantable cardioverter defibrillator, usually thought of as producing no or minimal effects on the defibrillation threshold. The current case report presents a patient with an endocardial implantable cardioverter defibrillator being treated with mexiletine, which precluded the ability to defibrillate the patient.

Original language	English
Pages (from-to)	507-508
Number of pages	2
Journal	PACE - Pacing and Clinical Electrophysiology
Volume	25
Issue number	4 I
DOIs	https://doi.org/10.1046/j.1460-9592.2002.00507.x
State	Published - 1 Jan 2002

Keywords

Defibrillation threshold
Implantable defibrillator
Mexiletine

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1046/j.1460-9592.2002.00507.x

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abstract = "Many antiarrhythmic drugs may produce a rise in defibrillation threshold. Mexiletine is a frequently used antiarrhythmic drug in patients with an implantable cardioverter defibrillator, usually thought of as producing no or minimal effects on the defibrillation threshold. The current case report presents a patient with an endocardial implantable cardioverter defibrillator being treated with mexiletine, which precluded the ability to defibrillate the patient.",

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AU - Katz, Amos

AU - Ilia, Reuven

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AB - Many antiarrhythmic drugs may produce a rise in defibrillation threshold. Mexiletine is a frequently used antiarrhythmic drug in patients with an implantable cardioverter defibrillator, usually thought of as producing no or minimal effects on the defibrillation threshold. The current case report presents a patient with an endocardial implantable cardioverter defibrillator being treated with mexiletine, which precluded the ability to defibrillate the patient.

KW - Defibrillation threshold

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KW - Mexiletine

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Mexiletine related chronic defibrillation threshold elevation: Case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

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