@inbook{4a9fb0e5431e447cae3057acb64b8d43,
title = "Microalgae as a source for VLC-PUFA production",
abstract = "Microalgae present a huge and still insufficiently tapped resource of very long-chain omega-3 and omega-6 polyunsaturated fatty acids (VLC-PUFA) for human nutrition and medicinal applications. This chapter describes the diversity of unicellular eukaryotic microalgae in respect to VLC-PUFA biosynthesis. Then, we outline the major biosynthetic pathways mediating the formation of VLC-PUFA by sequential desaturation and elongation of C18-PUFA acyl groups. We address the aspects of spatial localization of those pathways and elaborate on the role for VLC-PUFA in microalgal cells. Recent progress in microalgal genetic transformation and molecular engineering has opened the way to increased production efficiencies for VLC-PUFA. The perspectives of photobiotechnology and metabolic engineering of microalgae for altered or enhanced VLC-PUFA production are also discussed.",
keywords = "Biotechnology, Diversity, Lipid metabolism, Microalgae, Omega-3 LC-PUFA, Omega-6 LC-PUFA",
author = "Inna Khozin-Goldberg and Stefan Leu and Sammy Boussiba",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2016.",
year = "2016",
doi = "10.1007/978-3-319-25979-6_19",
language = "אנגלית",
isbn = "978-3-319-25977-2",
volume = "86",
series = "Sub-Cellular Biochemistry",
publisher = "Cham : Springer International Publishing : Imprint: Springer",
pages = "471--510",
booktitle = "Lipids in Plant and Algae Development",
}
