MIcrofluidic biofilm observation, analysis and treatment (MICRO-BOAT) platform

Y. W. Kim, M. P. Mosteller, M. T. Meyer, H. Ben-Yoav, W. E. Bentley, R. Ghodssi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

12 Scopus citations

Abstract

We present the first demonstration of a novel bacterial biofilm treatment technique showing a 56% average decrease in bacterial cell viability compared to traditional antibiotic treatments in a Micro-BOAT platform. Integrated linear array charge-coupled devices achieve spatially realized optical density monitoring, correlating to both average biomass and localized biofilm morphology. For on-chip demonstration of biofilm treatment, a unique bioelectric effect using a superpositioned direct and alternating current electric field is applied in the presence of antibiotics. Use of the platform demonstrated successful real-time monitoring of biofilm treatment and validated an on-chip bioelectric effect showing a decrease in both bacterial cell viability and overall biomass.

Original languageEnglish
Title of host publication2012 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2012
EditorsMehran Mehregany, David J. Monk
PublisherTransducer Research Foundation
Pages233-236
Number of pages4
ISBN (Electronic)9780964002494
DOIs
StatePublished - 1 Jan 2012
Externally publishedYes
Event2012 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2012 - Hilton Head, United States
Duration: 3 Jun 20127 Jun 2012

Publication series

NameTechnical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop

Conference

Conference2012 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2012
Country/TerritoryUnited States
CityHilton Head
Period3/06/127/06/12

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering
  • Hardware and Architecture

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