Microfluidic model of the blood brain barrier

Hamilton Geraldine (Inventor), Kerns Jordan (Inventor), Kerns Jordan (Inventor), Wen Norman (Inventor), Lucchesi Carol (Inventor), David Hinojosa Christopher (Inventor), Fraser Jacob (Inventor), Vatine Gad (Inventor), Sances Samuel (Inventor), Svendsen Clive (Inventor), Levner Daniel (Inventor), Sareen Dhruv (Inventor)

Research output: Patent


The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

Original languageEnglish
Patent numberGB2561312
IPCC12N 5/ 0797 A I
Priority date19/10/16
StatePublished - 10 Oct 2018


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