Abstract
The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.
Original language | English |
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Patent number | GB2561312 |
IPC | C12N 5/ 0797 A I |
Priority date | 19/10/16 |
State | Published - 10 Oct 2018 |