Microgels for efficient protein purification

Boaz Mizrahi; Silvia Irusta; Marshall McKenna; Cristina Stefanescu; Liron Yedidsion; Myatnoezin Myint; Robert Langer; Daniel S. Kohane

doi:10.1002/adma.201101258

Microgels for efficient protein purification

Boaz Mizrahi, Silvia Irusta, Marshall McKenna, Cristina Stefanescu, Liron Yedidsion, Myatnoezin Myint, Robert Langer, Daniel S. Kohane

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported.

Original language	English
Pages (from-to)	H258-H262
Journal	Advanced Materials
Volume	23
Issue number	36
DOIs	https://doi.org/10.1002/adma.201101258
State	Published - 22 Sep 2011
Externally published	Yes

Keywords

biomedical applications
colloids
microstructures
porous materials
proteins purification

ASJC Scopus subject areas

Materials Science (all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201101258

Cite this

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title = "Microgels for efficient protein purification",

abstract = "Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported.",

keywords = "biomedical applications, colloids, microstructures, porous materials, proteins purification",

author = "Boaz Mizrahi and Silvia Irusta and Marshall McKenna and Cristina Stefanescu and Liron Yedidsion and Myatnoezin Myint and Robert Langer and Kohane, {Daniel S.}",

year = "2011",

month = sep,

day = "22",

doi = "10.1002/adma.201101258",

language = "English",

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AU - Mizrahi, Boaz

AU - Irusta, Silvia

AU - McKenna, Marshall

AU - Stefanescu, Cristina

AU - Yedidsion, Liron

AU - Myint, Myatnoezin

AU - Langer, Robert

AU - Kohane, Daniel S.

PY - 2011/9/22

Y1 - 2011/9/22

N2 - Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported.

AB - Microgel particles with pore structure and ligands distributed evenly throughout their matrices overcome the major limitations of protein purification systems: low ligand density on the immobilized matrix and protein access to those ligands. A straightforward synthetic scheme for a highly efficient microgel matrix is reported.

KW - biomedical applications

KW - colloids

KW - microstructures

KW - porous materials

KW - proteins purification

UR - http://www.scopus.com/inward/record.url?scp=80053212402&partnerID=8YFLogxK

U2 - 10.1002/adma.201101258

DO - 10.1002/adma.201101258

M3 - Article

AN - SCOPUS:80053212402

SN - 0935-9648

VL - 23

SP - H258-H262

JO - Advanced Materials

JF - Advanced Materials

IS - 36

ER -

Microgels for efficient protein purification

Abstract

Keywords

ASJC Scopus subject areas

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