Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac

Robert Wilkes; Gang Wang; Carol Huang; Orly Yadid-Pecht; Martin P. Mintchev

doi:10.1109/ISCAS.2018.8351511

Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac

Robert Wilkes, Gang Wang, Carol Huang, Orly Yadid-Pecht, Martin P. Mintchev

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

2 Scopus citations

Abstract

This paper presents the eTac, a smart shoe for autonomous blood glucose monitoring (BGM) that aims at replacing finger-pricking tests used by diabetic patients. The device works as the user is walking: an actuator mechanism harnesses natural forces exerted by the user's body weight to drive an electronically-controlled lancet penetrating the skin at the toe tip, and to aid in the extraction of a whole blood sample from subcutaneous capillaries. The blood sample is then collected and blood glucose concentration (BGC) is measured directly from it in-situ. In-vivo human testing results demonstrate the feasibility of the method.

Original language	English
Title of host publication	2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers
ISBN (Electronic)	9781538648810
DOIs	https://doi.org/10.1109/ISCAS.2018.8351511
State	Published - 26 Apr 2018
Externally published	Yes
Event	2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Florence, Italy Duration: 27 May 2018 → 30 May 2018

Publication series

Name	Proceedings - IEEE International Symposium on Circuits and Systems
Volume	2018-May
ISSN (Print)	0271-4310

Conference

Conference	2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018
Country/Territory	Italy
City	Florence
Period	27/05/18 → 30/05/18

Keywords

MEMs
blood glucose monitoring
wearable device

ASJC Scopus subject areas

Electrical and Electronic Engineering

Access to Document

10.1109/ISCAS.2018.8351511

Cite this

Wilkes, R., Wang, G., Huang, C., Yadid-Pecht, O., & Mintchev, M. P. (2018). Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac. In 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings Article 8351511 (Proceedings - IEEE International Symposium on Circuits and Systems; Vol. 2018-May). Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/ISCAS.2018.8351511

Wilkes, Robert ; Wang, Gang ; Huang, Carol et al. / Minimally Invasive Pseudo-continuous Blood Glucose Monitoring : Results from In-Vitro and In-Vivo Testing of the eTac. 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings. Institute of Electrical and Electronics Engineers, 2018. (Proceedings - IEEE International Symposium on Circuits and Systems).

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title = "Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac",

abstract = "This paper presents the eTac, a smart shoe for autonomous blood glucose monitoring (BGM) that aims at replacing finger-pricking tests used by diabetic patients. The device works as the user is walking: an actuator mechanism harnesses natural forces exerted by the user's body weight to drive an electronically-controlled lancet penetrating the skin at the toe tip, and to aid in the extraction of a whole blood sample from subcutaneous capillaries. The blood sample is then collected and blood glucose concentration (BGC) is measured directly from it in-situ. In-vivo human testing results demonstrate the feasibility of the method.",

keywords = "MEMs, blood glucose monitoring, wearable device",

author = "Robert Wilkes and Gang Wang and Carol Huang and Orly Yadid-Pecht and Mintchev, {Martin P.}",

note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 ; Conference date: 27-05-2018 Through 30-05-2018",

year = "2018",

month = apr,

day = "26",

doi = "10.1109/ISCAS.2018.8351511",

language = "English",

series = "Proceedings - IEEE International Symposium on Circuits and Systems",

publisher = "Institute of Electrical and Electronics Engineers",

booktitle = "2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings",

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Wilkes, R, Wang, G, Huang, C, Yadid-Pecht, O & Mintchev, MP 2018, Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac. in 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings., 8351511, Proceedings - IEEE International Symposium on Circuits and Systems, vol. 2018-May, Institute of Electrical and Electronics Engineers, 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018, Florence, Italy, 27/05/18. https://doi.org/10.1109/ISCAS.2018.8351511

Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac. / Wilkes, Robert; Wang, Gang; Huang, Carol et al.
2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings. Institute of Electrical and Electronics Engineers, 2018. 8351511 (Proceedings - IEEE International Symposium on Circuits and Systems; Vol. 2018-May).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Y1 - 2018/4/26

N2 - This paper presents the eTac, a smart shoe for autonomous blood glucose monitoring (BGM) that aims at replacing finger-pricking tests used by diabetic patients. The device works as the user is walking: an actuator mechanism harnesses natural forces exerted by the user's body weight to drive an electronically-controlled lancet penetrating the skin at the toe tip, and to aid in the extraction of a whole blood sample from subcutaneous capillaries. The blood sample is then collected and blood glucose concentration (BGC) is measured directly from it in-situ. In-vivo human testing results demonstrate the feasibility of the method.

AB - This paper presents the eTac, a smart shoe for autonomous blood glucose monitoring (BGM) that aims at replacing finger-pricking tests used by diabetic patients. The device works as the user is walking: an actuator mechanism harnesses natural forces exerted by the user's body weight to drive an electronically-controlled lancet penetrating the skin at the toe tip, and to aid in the extraction of a whole blood sample from subcutaneous capillaries. The blood sample is then collected and blood glucose concentration (BGC) is measured directly from it in-situ. In-vivo human testing results demonstrate the feasibility of the method.

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KW - wearable device

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M3 - Conference contribution

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Wilkes R, Wang G, Huang C, Yadid-Pecht O, Mintchev MP. Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac. In 2018 IEEE International Symposium on Circuits and Systems, ISCAS 2018 - Proceedings. Institute of Electrical and Electronics Engineers. 2018. 8351511. (Proceedings - IEEE International Symposium on Circuits and Systems). doi: 10.1109/ISCAS.2018.8351511

Minimally Invasive Pseudo-continuous Blood Glucose Monitoring: Results from In-Vitro and In-Vivo Testing of the eTac

Abstract

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Keywords

ASJC Scopus subject areas

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