MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences

Ilia Zhidkov; Tal Nagar; Dan Mishmar; Eitan Rubin

doi:10.1016/j.mito.2011.08.005

MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences

Ilia Zhidkov, Tal Nagar, Dan Mishmar, Eitan Rubin

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

The use of Next-Generation Sequencing of mitochondrial DNA is becoming widespread in biological and clinical research. This, in turn, creates a need for a convenient tool that detects and analyzes heteroplasmy. Here we present MitoBamAnnotator, a user friendly web-based tool that allows maximum flexibility and control in heteroplasmy research. MitoBamAnnotator provides the user with a comprehensively annotated overview of mitochondrial genetic variation, allowing for an in-depth analysis with no prior knowledge in programming.

Original language	English
Pages (from-to)	924-928
Number of pages	5
Journal	Mitochondrion
Volume	11
Issue number	6
DOIs	https://doi.org/10.1016/j.mito.2011.08.005
State	Published - 1 Nov 2011

Keywords

Annotation
Heteroplasmy
Mitochondrial DNA
Next generation sequence

ASJC Scopus subject areas

Molecular Medicine
Molecular Biology
Cell Biology

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10.1016/j.mito.2011.08.005

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title = "MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences",

abstract = "The use of Next-Generation Sequencing of mitochondrial DNA is becoming widespread in biological and clinical research. This, in turn, creates a need for a convenient tool that detects and analyzes heteroplasmy. Here we present MitoBamAnnotator, a user friendly web-based tool that allows maximum flexibility and control in heteroplasmy research. MitoBamAnnotator provides the user with a comprehensively annotated overview of mitochondrial genetic variation, allowing for an in-depth analysis with no prior knowledge in programming.",

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author = "Ilia Zhidkov and Tal Nagar and Dan Mishmar and Eitan Rubin",

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AU - Nagar, Tal

AU - Mishmar, Dan

AU - Rubin, Eitan

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AB - The use of Next-Generation Sequencing of mitochondrial DNA is becoming widespread in biological and clinical research. This, in turn, creates a need for a convenient tool that detects and analyzes heteroplasmy. Here we present MitoBamAnnotator, a user friendly web-based tool that allows maximum flexibility and control in heteroplasmy research. MitoBamAnnotator provides the user with a comprehensively annotated overview of mitochondrial genetic variation, allowing for an in-depth analysis with no prior knowledge in programming.

KW - Annotation

KW - Heteroplasmy

KW - Mitochondrial DNA

KW - Next generation sequence

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MitoBamAnnotator: A web-based tool for detecting and annotating heteroplasmy in human mitochondrial DNA sequences

Abstract

Keywords

ASJC Scopus subject areas

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