Mitochondrial Networking in T Cell Memory

Marc Liesa; Orian S. Shirihai

doi:10.1016/j.cell.2016.06.035

Mitochondrial Networking in T Cell Memory

Marc Liesa, Orian S. Shirihai

Research output: Contribution to journal › Short survey › peer-review

16 Scopus citations

Abstract

T-lymphocytes show large changes in ATP demand and nutrient utilization, imposed by their different roles as T memory and T effector cells. Therefore, T cell remodeling represents a bioenergetic challenge to mitochondria. New work from Buck et al. links changes in mitochondrial shape to T cell fate choice.

Original language	English
Pages (from-to)	9-10
Number of pages	2
Journal	Cell
Volume	166
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2016.06.035
State	Published - 1 Jan 2016
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2016.06.035

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title = "Mitochondrial Networking in T Cell Memory",

abstract = "T-lymphocytes show large changes in ATP demand and nutrient utilization, imposed by their different roles as T memory and T effector cells. Therefore, T cell remodeling represents a bioenergetic challenge to mitochondria. New work from Buck et al. links changes in mitochondrial shape to T cell fate choice.",

author = "Marc Liesa and Shirihai, {Orian S.}",

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AU - Liesa, Marc

AU - Shirihai, Orian S.

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AB - T-lymphocytes show large changes in ATP demand and nutrient utilization, imposed by their different roles as T memory and T effector cells. Therefore, T cell remodeling represents a bioenergetic challenge to mitochondria. New work from Buck et al. links changes in mitochondrial shape to T cell fate choice.

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U2 - 10.1016/j.cell.2016.06.035

DO - 10.1016/j.cell.2016.06.035

M3 - Short survey

C2 - 27368094

AN - SCOPUS:84982163263

SN - 0092-8674

VL - 166

SP - 9

EP - 10

JO - Cell

JF - Cell

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ER -

Mitochondrial Networking in T Cell Memory

Abstract

ASJC Scopus subject areas

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