In earlier reports it was demonstrated that when small magnetic spheres or cylinders were embedded within polymer matrices impregnated with bovine serum album (BSA), rates of BSA release could be increased by the application of an oscillating magnetic field to these samples. This paper now reports on the implementation of an electromagnetic field source and greater control over the system parameters, examination of the dynamics of release regulation (e. g. timecourse of modulated events, stability of baseline and elevated levels), and a study of the effect of varying the amplitude of the magnetic field on modulated release both in vitro and in vivo.
|Number of pages||5|
|Journal||Transactions - American Society for Artificial Internal Organs|
|State||Published - 1 Dec 1984|