Molecular cloning and characterization of PKCθ, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells

Immunology and Microbiology

• Hematopoietic Cell 100%
• Molecular Cloning 100%
• Multigene Family 100%
• Polymerase Chain Reaction 75%
• Amino Acid Sequence 75%
• T Cell 50%
• Cell Line 50%
• Signal Transduction 25%
• Carcinoma Cell Line 25%
• Thymocyte 25%
• Open Reading Frame 25%
• Testis 25%
• DNA Sequence 25%
• Peripheral Blood Lymphocyte 25%
• Cell Lysate 25%
• Enzyme Active Site 25%
• Rabbit Antiserum 25%
• DNA Library 25%
• Consensus Sequence 25%
• Conserved Sequence 25%
• C2 Domain 25%
• Hematopoietic Tissue 25%

Keyphrases

• Protein Kinase 100%
• Molecular Characterization 100%
• Gene Family 100%
• GC Gene 100%
• Molecular Cloning 100%
• Hematopoietic Cells 100%
• Complementary DNA (cDNA) 26%
• Protein Kinase C Isoforms 15%
• Polymerase Chain Reaction 10%
• Novel Protein Kinase C 10%
• T Cells 5%
• T Cell Lines 5%
• Signal Transduction 5%
• DNA Sequencing 5%
• Expressed Protein 5%
• Expression Level 5%
• Coding Sequence 5%
• Thymocytes 5%
• Polymerase Chain Reaction Analysis 5%
• Ca2+-independent 5%
• Testicle 5%
• Amino Acid Sequence 5%
• Catalytic Domain 5%
• Upstream Open Reading Frame (uORF) 5%
• Serine-threonine Kinase 5%
• Jurkat Cells 5%
• Ca2+ Binding 5%
• Human Peripheral Blood Lymphocytes 5%
• Growth Regulators 5%
• Regulatory Pathways 5%
• Consensus Sequence 5%
• Cell Lysate 5%
• C2 Domain 5%
• Degenerate Oligonucleotide Primer 5%
• Human Carcinoma Cells 5%
• Domain Structure 5%
• Sequence Comparison 5%
• Sequence Structure 5%
• Mammalian Proteins 5%
• Jurkat 5%
• Core Sequence 5%
• Conserved Sequence 5%
• Rabbit Antiserum 5%
• Hematopoietic Tissue 5%
• V3 Domain 5%
• Leukemic T-cells 5%
• Partial Core 5%
• RNase Protection 5%
• Sequence Characteristics 5%

Biochemistry, Genetics and Molecular Biology

• Multigene Family 100%
• Protein Kinase C 100%
• Molecular Cloning 100%
• Isoform 25%
• Peptide Sequence 15%
• Polymerase Chain Reaction 15%
• Protein Kinases 10%
• T Cell 10%
• Enzyme 5%
• DNA Sequence 5%
• Oligonucleotide 5%
• Signal Transduction 5%
• Serine 5%
• Threonine 5%
• Thymocyte 5%
• Enzyme Active Site 5%
• Open Reading Frame 5%
• Cell Lysate 5%
• Leporidae 5%
• Sequence Motif 5%
• Consensus Sequence 5%
• Peripheral Blood Lymphocyte 5%
• Ribonuclease 5%
• C2 Domain 5%
• DNA Library 5%
• Conserved Sequence 5%