Multi-omics analysis of early leaf development in Arabidopsis thaliana

Mohammad Amin Omidbakhshfard, Ewelina M. Sokolowska, Valerio Di Vittori, Leonardo Perez de Souza, Anastasiya Kuhalskaya, Yariv Brotman, Saleh Alseekh, Alisdair R. Fernie, Aleksandra Skirycz

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The growth of plant organs is driven by cell division and subsequent cell expansion. The transition from proliferation to expansion is critical for the final organ size and plant yield. Exit from proliferation and onset of expansion is accompanied by major metabolic reprogramming, and in leaves with the establishment of photosynthesis. To learn more about the molecular mechanisms underlying the developmental and metabolic transitions important for plant growth, we used untargeted proteomics and metabolomics analyses to profile young leaves of a model plant Arabidopsis thaliana representing proliferation, transition, and expansion stages. The dataset presented represents a unique resource comprising approximately 4,000 proteins and 300 annotated small-molecular compounds measured across 6 consecutive days of leaf growth. These can now be mined for novel developmental and metabolic regulators of plant growth and can act as a blueprint for studies aimed at better defining the interface of development and metabolism in other species.

Original languageEnglish
Article number100235
JournalPatterns
Volume2
Issue number4
DOIs
StatePublished - 9 Apr 2021

Keywords

  • 12-OPDA
  • DSML 1: Concept: Basic principles of a new data science output observed and reported
  • leaf development
  • metabolomics
  • mitotic arrest
  • proteomics

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