Multi-Omics and Integrative Approach towards Understanding Salinity Tolerance in Rice: A Review

Pandiyan Muthuramalingam, Rajendran Jeyasri, Kasinathan Rakkammal, Lakkakula Satish, Sasanala Shamili, Adhimoolam Karthikeyan, Alaguvel Valliammai, Arumugam Priya, Anthonymuthu Selvaraj, Pandiyan Gowri, Qiang Sheng Wu, Shunmugiah Karutha Pandian, Hyunsuk Shin, Jen Tsung Chen, Venkidasamy Baskar, Muthu Thiruvengadam, Manoharan Akilan, Manikandan Ramesh

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Rice (Oryza sativa L.) plants are simultaneously encountered by environmental stressors, most importantly salinity stress. Salinity is the major hurdle that can negatively impact growth and crop yield. Understanding the salt stress and its associated complex trait mechanisms for enhancing salt tolerance in rice plants would ensure future food security. The main aim of this review is to provide insights and impacts of molecular-physiological responses, biochemical alterations, and plant hormonal signal transduction pathways in rice under saline stress. Furthermore, the review highlights the emerging breakthrough in multi-omics and computational biology in identifying the saline stress-responsive candidate genes and transcription factors (TFs). In addition, the review also summarizes the biotechnological tools, genetic engineering, breeding, and agricultural practicing factors that can be implemented to realize the bottlenecks and opportunities to enhance salt tolerance and develop salinity tolerant rice varieties. Future studies pinpointed the augmentation of powerful tools to dissect the salinity stress-related novel players, reveal in-depth mechanisms and ways to incorporate the available literature, and recent advancements to throw more light on salinity responsive transduction pathways in plants. Particularly, this review unravels the whole picture of salinity stress tolerance in rice by expanding knowledge that focuses on molecular aspects.

Original languageEnglish
Article number1022
Issue number7
StatePublished - 1 Jul 2022


  • agricultural practices
  • bioinformatics
  • biotechnological tools
  • breeding
  • multi-omics
  • rice
  • salinity stress
  • transcription factors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)
  • Immunology and Microbiology (all)
  • Agricultural and Biological Sciences (all)


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