Multi-peak phenomenon of insect cell infection with baculovirus at low multiplicity of infection

You Hong Zhang

doi:10.1111/j.1745-7270.2005.00115.x

Multi-peak phenomenon of insect cell infection with baculovirus at low multiplicity of infection

You Hong Zhang

Department of Chemical Engineering

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

In this communication we report the infection of armyworm Spodoptera frugiperda IPLB-Sf-21 cells with Anticarsia gemmatalis multicapsid nucleopolyhedrovirus at low multiplicity of infection (MOI). The temporal variation of the extra-cellular virus and of the unstained cell was followed. The series of peaks in the virus concentration and the unstained cells count were used in order to infer the dynamic mechanism of the infection at low MOI. This mechanism can be used as the basis for the future formulation of a mathematical model of the process.

Original language	English
Pages (from-to)	857-861
Number of pages	5
Journal	Acta Biochimica et Biophysica Sinica
Volume	37
Issue number	12
DOIs	https://doi.org/10.1111/j.1745-7270.2005.00115.x
State	Published - 1 Dec 2005

Keywords

Anticarsia gemmatalis multicapsid nucleopolyhedrovirus (AgMNPV)
Dynamics
Infection
Insect cell
Multiplicity of infection (MOI)

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

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10.1111/j.1745-7270.2005.00115.x

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title = "Multi-peak phenomenon of insect cell infection with baculovirus at low multiplicity of infection",

abstract = "In this communication we report the infection of armyworm Spodoptera frugiperda IPLB-Sf-21 cells with Anticarsia gemmatalis multicapsid nucleopolyhedrovirus at low multiplicity of infection (MOI). The temporal variation of the extra-cellular virus and of the unstained cell was followed. The series of peaks in the virus concentration and the unstained cells count were used in order to infer the dynamic mechanism of the infection at low MOI. This mechanism can be used as the basis for the future formulation of a mathematical model of the process.",

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AB - In this communication we report the infection of armyworm Spodoptera frugiperda IPLB-Sf-21 cells with Anticarsia gemmatalis multicapsid nucleopolyhedrovirus at low multiplicity of infection (MOI). The temporal variation of the extra-cellular virus and of the unstained cell was followed. The series of peaks in the virus concentration and the unstained cells count were used in order to infer the dynamic mechanism of the infection at low MOI. This mechanism can be used as the basis for the future formulation of a mathematical model of the process.

KW - Anticarsia gemmatalis multicapsid nucleopolyhedrovirus (AgMNPV)

KW - Dynamics

KW - Infection

KW - Insect cell

KW - Multiplicity of infection (MOI)

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JO - Acta Biochimica et Biophysica Sinica

JF - Acta Biochimica et Biophysica Sinica

IS - 12

ER -

Multi-peak phenomenon of insect cell infection with baculovirus at low multiplicity of infection

Abstract

Keywords

ASJC Scopus subject areas

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