Multiple micromanipulations for preimplantation genetic diagnosis do not affect embryo development to the blastocyst stage

Jeanine Cieslak-Janzen, Ilan Tur-Kaspa, Yuri Ilkevitch, Alejandra Bernal, Randy Morris, Yury Verlinsky

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

To determine the impact of multiple micromanipulation procedures for preimplantation genetic diagnosis (PGD) on embryo development, a retrospective analysis was performed of 9,925 embryos (862 PGD cycles), which were compared with 28,126 nonbiopsied embryos (2,751 consecutive intracytoplasmic sperm injection [ICSI] cycles) from the same time period. Because fertilization rates, the proportion of embryos with ≥ 6 cells on day 3, and blastocyst rates were similar in the PGD and control groups, we conclude that multiple micromanipulations on oocytes and embryos can be performed safely for PGD.

Original languageEnglish
Pages (from-to)1826-1829
Number of pages4
JournalFertility and Sterility
Volume85
Issue number6
DOIs
StatePublished - 1 Jun 2006
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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